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Tapentadol, sold under the brand name Nucynta among others, is a strong painkiller which works in two ways. It binds to certain receptors in your brain and spinal cord, and it also regulates the level of a chemical called noradrenaline in your brain.

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Tapentadol: Uses, Dosage, Side Effects, Warnings | Medicine24hrs.com

Buy Cheapest Painkiller Tapentadol online

Tapentadol, sold under the brand name Nucynta among others, is a strong painkiller which works in two ways. It binds to certain receptors (called opioid receptors) in your brain and spinal cord, and it also regulates the level of a chemical called noradrenaline in your brain. These actions together reduce the pain you feel.

Tapentadol is used to ease pain which cannot be managed with other types of painkillers.

 Which medicine is best in between Tapentadol Vs Tramadol ?

tapentadol and tramadol drugss are considered opioid agonists, but tramadol is weaker than tapentadol. Both inhibit reuptake of norepinephrine to roughly the same amount, but tramadol inhibits serotonin re uptake 2 times more than tapentadol.

What is more tolerable Tapentadol or Oxycodone?

Tapentadol and Oxycodone are effective in chronic in severe pain and tapentadol and oxycodone have shown advantage in gastrointestinal bearability versus oxycodone. Therefore, it is of high scientific interest to compare the latter two analgesics with respect to gastrointestinal bearability.

What Is TAPENTADOL® ER is:

  • A strong prescription pain medicine that contains an opioid (narcotic) that is used to manage pain severe enough to require daily around-the-clock, long-term treatment with an opioid, when other pain treatments such as non-opioid pain medicines or immediate-release opioid medicines do not treat your pain well enough or you cannot tolerate them.
  • Also used to manage pain from damaged nerves (neuropathic pain) that happens with diabetes and is severe enough to require daily around-the-clock, long-term treatment with an opioid, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them.
  • A long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death.
  • Not used to treat pain that is not around-the-clock pain.

Important information about Nucynta-ER:

  • Get emergency help right away if you take too much Nucynta-ER (overdose). When you first start taking Nucynta-ER, when your dose is changed, or if you take too much (overdose), serious or life threatening breathing problems that can lead to death may occur.
  • Taking Nucynta-ER with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.
  • Never give anyone your Nucynta-ER. They could die from taking it. Store Nucynta-ER away from children and in a safe place to prevent stealing or abuse. Selling or giving away Nucynta-ER is against the law.

Do not take Nucynta-ER if you have:

  • Severe asthma, trouble breathing, or other lung problems.
  • A bowel blockage or have narrowing of the stomach or intestines.

Before taking TAPENTADOL ER, tell your healthcare provider if you have a history of:

  • Head injury, seizures
  • Problems urinating
  • Abuse of street or prescription drugs, alcohol addiction, or mental health problems.
  • Liver, kidney, thyroid problems
  • Pancreas or gallbladder problems

Tell your healthcare provider if you are:

  • Pregnant or planning to become pregnant. Prolonged use of Nucynta-ER during pregnancy can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized and treated.
  • Breastfeeding. Not recommended during treatment with Nucynta-ER. It may harm your baby.
  • Taking prescription or over-the-counter medicines, vitamins, or herbal supplements. Taking Nucynta-ER with certain other medicines can cause serious side effects.

When taking Nucynta-ER:

  • Do not change your dose. Take Nucynta-ER exactly as prescribed by your healthcare provider. Use the lowest effective dose for the shortest time needed.
  • Take your prescribed dose every 12 hours, at the same time every day. Do not take more than your prescribed dose in 24 hours. If you miss a dose, take your next dose at your usual time.
  • Swallow Nucynta-ER whole. Do not cut, break, chew, crush, dissolve, snort, or inject Nucynta-ER because this may cause you to overdose and die.
  • Call your healthcare provider if the dose you are taking does not control your pain.
  • Do not stop taking Nucynta-ER without talking to your healthcare provider.
  • After you stop taking Nucynta-ER, flush any unused tablets down the toilet.

TAPENTADOL® ER IMPORTANT SAFETY INFORMATION

WARNING: ADDICTION, ABUSE, AND MISUSE; RISK EVALUATION AND MITIGATION STRATEGY (REMS); LIFE‑THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; NEONATAL OPIOID WITHDRAWAL SYNDROME; INTERACTION WITH ALCOHOL and RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

Addiction, Abuse, and Misuse

TAPENTADOL ER exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient’s risk prior to prescribing TAPENTADOL-ER, and monitor all patients regularly for the development of these behaviors and conditions.

Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS)

To ensure that the benefits of opioid analgesics outweigh the risks of addiction, abuse, and misuse, the Food and Drug Administration (FDA) has required a REMS for these products. Under the requirements of the REMS, drug companies with approved opioid analgesic products must make REMS‑compliant education programs available to healthcare providers. Healthcare providers are strongly encouraged to:

  • complete a REMS‑compliant education program,
  • counsel patients and/or their caregivers, with every prescription, on safe use, serious risks, storage, and disposal of these products,
  • emphasize to patients and their caregivers the importance of reading the Medication Guide every time it is provided by their pharmacist, and
  • consider other tools to improve patient, household, and community safety.

Life-Threatening Respiratory Depression

Serious, life‑threatening, or fatal respiratory depression may occur with use of TAPENTADOL-ER. Monitor for respiratory depression, especially during initiation of TAPENTADOL-ER or following a dose increase. Instruct patients to swallow TAPENTADOL ER tablets whole; crushing, chewing, or dissolving TAPENTADOL ER tablets can cause rapid release and absorption of a potentially fatal dose of tapentadol.

Accidental Ingestion

Accidental ingestion of even one dose of TAPENTADOL ER, especially by children, can result in a fatal overdose of tapentadol.

Neonatal Opioid Withdrawal Syndrome

Prolonged use of TAPENTADOL ER during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.

Interaction With Alcohol

Instruct patients not to consume alcoholic beverages or use prescription or non-prescription products that contain alcohol while taking TAPENTADOL-ER. The co-ingestion of alcohol with TAPENTADOL-ER may result in increased plasma tapentadol levels and a potentially fatal overdose of tapentadol.

Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressants

Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death.

  • Reserve concomitant prescribing of TAPENTADOL-ER and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate.
  • Limit dosages and durations to the minimum required.
  • Follow patients for signs and symptoms of respiratory depression and sedation.

While taking TAPENTADOL ER DO NOT:

  • Drive or operate heavy machinery until you know how TAPENTADOL ER affects you. TAPENTADOL ER can make you sleepy, dizzy, or lightheaded.
  • Drink alcohol, or use prescription or over-the-counter medicines containing alcohol. Using products containing alcohol during treatment with TAPENTADOL ER may cause you to overdose and die.

The possible side effects of TAPENTADOL ER are:

  • Constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.

Get emergency medical help if you have:

  • Trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, light-headedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.
  • Agitation, hallucinations, coma, feeling overheated, or heavy sweating.

These are not all the possible side effects of TAPENTADOL ER. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1‑800‑FDA‑1088. For more information go to dailymed.nlm.nih.gov

Please see full Prescribing Information, including Boxed Warning and Medication Guide, or speak to your healthcare provider if you have questions about TAPENTADOL ER.

 

TAPENTADOL® TABLETS are:

  • A strong prescription pain medicine that contains an opioid (narcotic) that is used to manage short term (acute) pain in adults, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them.
  • An opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death.

TAPENTADOL® TABLETS IMPORTANT SAFETY INFORMATION

Important information about TAPENTADOL tablets:

  • Get emergency help right away if you take too much TAPENTADOL (overdose) tablets. When you first start taking TAPENTADOL tablets, when your dose is changed, or if you take too much (overdose), serious or life-threatening breathing problems that can lead to death may occur.
  • Taking TAPENTADOL tablets with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.
  • Never give anyone else your TAPENTADOL tablets. They could die from taking it. Store TAPENTADOL tablets away from children and in a safe place to prevent stealing or abuse. Selling or giving away TAPENTADOL tablets is against the law.

Do not take TAPENTADOL tablets if you have:

  • Severe asthma, trouble breathing, or other lung problems.
  • A bowel blockage or have narrowing of the stomach or intestines.

Before taking TAPENTADOL tablets, tell your healthcare provider if you have a history of:

  • Head injury, seizures
  • Problems urinating
  • Abuse of street or prescription drugs, alcohol addiction, or mental health problems.
  • Liver, kidney, thyroid problems
  • Pancreas or gallbladder problems

Tell your healthcare provider if you are:

  • Pregnant or planning to become pregnant. Prolonged use of TAPENTADOL tablets during pregnancy can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized and treated.
  • Breastfeeding. TAPENTADOL tablets pass into breast milk and may harm your baby.
  • Taking prescription or over-the-counter medicines, vitamins, or herbal supplements. Taking TAPENTADOL tablets with certain other medicines can cause serious side effects that could lead to death.

When taking TAPENTADOL tablets:

    • Do not change your dose. Take TAPENTADOL tablets exactly as prescribed by your healthcare provider. Use the lowest dose possible for the shortest time needed.
    • Take your prescribed dose every 4-6 hours, at the same time every day. Do not take more than your prescribed dose.
    • Call your healthcare provider if the dose you are taking does not control your pain.
    • If you have been taking TAPENTADOL tablets regularly, do not stop taking TAPENTADOL tablets without talking to your healthcare provider.
  • After you stop taking TAPENTADOL tablets, flush any unused tablets down the toilet.

TAPENTADOL® TABLETS IMPORTANT SAFETY INFORMATION

WARNING: ADDICTION, ABUSE, AND MISUSE; RISK EVALUATION AND MITIGATION STRATEGY (REMS); LIFE‑THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

Addiction, Abuse, and Misuse

TAPENTADOL tablets expose patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient’s risk prior to prescribing TAPENTADOL tablets, and monitor all patients regularly for the development of these behaviors and conditions.

Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS)

To ensure that the benefits of opioid analgesics outweigh the risks of addiction, abuse, and misuse, the Food and Drug Administration (FDA) has required a REMS for these products. Under the requirements of the REMS, drug companies with approved opioid analgesic products must make REMS‑compliant education programs available to healthcare providers. Healthcare providers are strongly encouraged to:

  • complete a REMS‑compliant education program,
  • counsel patients and/or their caregivers, with every prescription, on safe use, serious risks, storage, and disposal of these products,
  • emphasize to patients and their caregivers the importance of reading the Medication Guide every time it is provided by their pharmacist, and
  • consider other tools to improve patient, household, and community safety.

Life-Threatening Respiratory Depression

Serious, life‑threatening, or fatal respiratory depression may occur with use of TAPENTADOL tablets. Monitor for respiratory depression, especially during initiation of TAPENTADOL tablets or following a dose increase.

Accidental Ingestion

Accidental ingestion of even one dose of TAPENTADOL tablets, especially by children, can result in a fatal overdose of tapentadol.

Neonatal Opioid Withdrawal Syndrome

Prolonged use of TAPENTADOL tablets during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life‑threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.

Risks From Concomitant Use With Benzodiazepines Or Other CNS Depressants

Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death.

    • Reserve concomitant prescribing of TAPENTADOL tablets and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate.
    • Limit dosages and durations to the minimum required.
  • Follow patients for signs and symptoms of respiratory depression and sedation.

FAQ

 

While taking TAPENTADOL100mg tablets DO NOT:

  • Drive or operate heavy machinery, until you know how TAPENTADOL tablets affect you. TAPENTADOL tablets can make you sleepy, dizzy, or lightheaded.
  • Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. Using products containing alcohol during treatment with TAPENTADOL tablets may cause you to overdose and die.

The possible side effects of #TAPENTADOL 100mg tablets:

  • Constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, abdominal pain. Call your healthcare provider if you have any of these symptoms and they are severe.

Get emergency medical help if you have:

  • Trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue, or throat, extreme drowsiness, light-headedness when changing positions, feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

 

 

 

1 review for Tapentadol 100MG

  1. Tramadol lover

    Is Tapentadol alternative of Tramadol 225mg?

    • Robert Eve

      Yes, Tapentadol is alternative of Tramadol.

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